hrp0097p1-166 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2023

Treatment with triptorelin and estradiol in transgender girls. should we use SDS for assigned sex or SDS for affirmed gender?

Rica Itxaso , Sánchez Amaia , Peña Asier , Grau Gema , Vela Amaia , Luisa Guadilla Maria

Introduction: International guidelines recommend puberty blocking using GnRH analogs and subsequent association with estrogen therapy in transgender girls who require for medical treatment. They have been shown to have a bone mineral density calculated as standard deviation score (BMD-SDS) for their assigned sex lower than the mean at baseline, and there is a potential risk of impairing peak bone mass as treatment result.Objectiv...